ONCOMATE

These biomarkers are identified and quantified by methods relying on their recognition by their respective antibodies. However, the production of antibodies specific of a given protein requires successive long and costly biotechnogical steps. In addition, the detection of the proteinantibody complexation requires also a complex step for labeling the antibody with a "tag" allowing its detection by suitable equipment. The aim of the ONCOMATE project is to develop an innovative technological platform for the identification and the monitoring of cancer biomarkers that bypasses both antibodies requirement and labeling kit or enzymatic device for their detection. For this purpose, a new king of "Biochips" will be set up, including three innovative technologies. The first one relates to the development of a new sensor able to detect the protein using nanotechnologies, the second one relates to the detector set up, allowing to "read" the biochips, and the third one relates to the signal processing by machine learning. With such a device, we hope that it will be possible to facilitate the biological analyses implemented for making the diagnosis and during the treatment of the disease.